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Fragment 176-191 peptide is a short segment of human growth hormone (HGH) and is sometimes referred to as the "lipolytic fragment." The name was coined due to research which has proven that Fragment 176-191 enhances fat metabolism. Studies have shown that the synthetic fragment enhances the lipolytic effects of HGH, hence the peptide can be used for an anti-obesity treatment.
The principle areas of research on Fragment 176-191 peptide explores its role in fat metabolism and weight loss. The findings have led to further research on the interesting domain of the mechanism of energy homeostasis in the body. The secondary areas of interest include the effects of Fragment 176-191 in the repair of cartilage and connective tissue regeneration.
Benefits of Fragment HGH 176-191:
1. Burning of fat and weight loss
The fat-burning action of Fragment 176-191 peptide is brought about by increasing the production of beta-3 adrenergic receptors (3-AR or ADRB3). Agonist activity of the fragment upon interaction with ADRB3 directly enhances fat burning in adipose tissue and triggers thermogenesis in skeletal muscle
2. Decrease in blood sugar
The screening of at least 6 different fragments obtained from the C terminal section of HGH has shown that fragment 176-191 is the most effective synthetic derivative of HGH for decreasing blood sugar levels.
3. Promotion of cartilage regeneration
Among other beneficial effects of Fragment 176-191 is the ability of cartilage regeneration. Studies have shown that peptides could bring about cartilage regeneration, in turn Fragment 176-191 can help improve the conditions of osteoarthritis (AKA wear and tear arthritis). Thus there is the scope of better and more beneficial treatment of osteoarthritis involving this synthetic fragment.
Buy a 1 month supply for $139, or if you buy a 2 month supply for $278 we'll give you a 3rd for free!
First, what are peptides? They are defined as a compound of two or more amino acids in which a carboxyl group of one is united with an amino group of another. With the elimination of a molecule of water, a peptide bond is formed. Simply put, they are basically just small proteins. Technically, anything with fewer than 50 amino acids is considered a peptide although this is not a hard and fast rule. A di-peptide is made up of two amino acids joined by one peptide bond. Tri-peptides are three amino acids bound by two peptides. So forth and so on. A polypeptide is just a long, unbranched chain of amino acids joined by peptide bonds that is not complex enough to be referred to as a protein. (Proteins are made up of polypeptides.)
Peptides, as we mentioned are made from amino acids. So, intake and production of amino acids is necessary for production of all the peptides needed for the body to work efficiently. Of course, as we age and we go through different times in our lives with different diets, stress, and physical changes some essential amino acids and peptide production is down-regulated. For example, insulin-like growth factor (IGF-1) production is reduced naturally when we are stressed and also as we age. Peptides have many functions in the body, some act like neurotransmitters, others like hormones. Many control and influence how our bodies react to diet and physical exercise. There are also several amino acids that are necessary in a sufficient amount to produce hormones like human growth hormone (HGH). If you aren’t absorbing or making enough of those amino acids, your production of that hormone will be lowered. Those of us interested in fitness and athletic goals, of course, are interested in counteracting these down-regulations so that we can maximize our bodies ability to recover, perform, and meet athletic goals.
Amino acid supplementation is pretty common among fitness buffs, but peptide supplementation is becoming more common. What’s the advantage? Well, peptides are digested and used more readily by the body as they are smaller and your body doesn’t have to break down a larger molecule. Also, peptides are more stable in the body and therefore more beneficial than unstable, unbonded amino acids.